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Benefits of SGLT2 Inhibitors beyond glycemic control a focus on metabolic, cardiovascular, and renal outcomes

Anti-ferroptosis: synergistic regulation of oxidative stress and iron metabolism Ferroptosis is a type of programmed cell death that depends on iron ions and lipid peroxidation, and it plays a key role in IRI

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These side effects can have significant health consequences if not promptly addressed

This may be, in part, due to the facilitation of aerobic metabolism of lipids in skeletal muscles as a result of increased mitochondria biogenesis and decreased muscle acidosis