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The World Anti-Doping Agency (WADA) added BPC-157 to its Prohibited List in 2022 under the S0 category (Non-Approved Substances)

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A pivotal RCT in 116 cannabis-dependent adolescents found that NAC (1,200 mg twice daily) more than doubled the odds of a negative urine cannabinoid test compared to placebo (OR 2.4, 95% CI 1.1-5.2) (Gray et al., Am J Psychiatry, 2012) [76]

Important limitations remain: The human studies are small