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By maintaining mitochondrial homeostasis and reducing oxidative stress, 2-APQC emerges as a potential candidate for treating heart failure and related cardiac conditions 188

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Metabolomic profiling revealed that the granules modulated several key metabolic pathways, including purine metabolism, thereby offering important leads for target identification [542]

These results suggested that chronic hypoxia promoted the expression of Acer2 by activating HIF-2

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