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Canonical and non-canonical effects of the NLRP3 inflammasome in kidney inflammation and fibrosis

These advances have driven widespread adoption in metabolic disease, where GLP-1 RAs improve glycaemic control, support significant weight loss, and reduce cardiovascular risk

An estimated 20% of obese patients have minimal or no response to GLP-1s and around 40% stop treatment after 12 months mostly due to shortages, dosage inconvenience3 and costs

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Low levels of glutathione make us susceptible to free radicals that cause cancers, infections, autoimmune diseases, asthma, and neurological conditions such as Parkinsons, MS, and Alzheimers