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SKU: 95840003303

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World J Diabetes 10(1):115

Fatigue represents an underappreciated side effect that affects some patients

Specifically, in skeletal muscle, age-associated reductions in NRF2 target gene expression is accompanied by increased hydrogen peroxide and 4-hydroxynonenal (4-HNE) production, glutathione depletion, and oxidant damage (Safdar et al., 2010)