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Nature Reviews Endocrinology

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DIABETOLOGY / CLINICAL RESEARCH The effects of oral trehalose on glycaemia, inflammation, and quality of life in patients with type 2 diabetes: a pilot randomized controlled trial More details Hide details 1 Applied Biomedical Research Centre, Mashhad University of Medical Sciences, Mashhad, Iran 2 Nutrition and Food Security Research Centre and Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran 3 Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran 4 Department of Medical Biotechnology and Nanotechnology, Mashhad University of Medical Sciences, Mashhad, Iran 5 Department of Community Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 6 School of Postgraduate Studies and Research, RCSI Medical University of Bahrain, Busaiteen, Bahrain 7 Department of Preventive Cardiology, Medical University of Lodz (MUL), Lodz, Poland 8 Cardiovascualr Research Centre, University of Zielona Gora, Zielona Gora, Poland 9 Department of Cardiology and Congenital Diseases of Adults, Polish Mothers Memorial Hospital Research Institute (PMMHRI), Lodz, Poland 10 Anesthesia and Critical Care Research Centre, Isfahan University of Medical Sciences, Isfahan, Iran 11 Department of Traditional Pharmacy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran 12 Biotechnology Research Centre, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran 13 School of Medicine, The University of Western Australia, Perth, Australia 14 Department of Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran Submission date: 2022-12-17 Final revision date: 2023-01-05 Acceptance date: 2023-01-05 Online publication date: 2023-01-05 Publication date: 2023-11-13 Arch Med Sci 2023;19(6):1693-1700 KEYWORDS TOPICS ABSTRACT Introduction: Trehalose is a naturally occurring disaccharide of 2 glucose molecules, which has been suggested as a potential therapeutic agent to reduce blood glucose and ameliorate diabetes-related complications in type 2 diabetes (T2D)

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