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The study also found major adverse cardiovascular eventslike heart attack or failureoccurred less frequently than anticipated. Retatrutide is considered likely the most powerful weight loss drug yet, as it targets multiple hormonesGLP-1, GIP and glucagonthat impact appetite and metabolism, whereas other drugs currently on the market target one or two of those hormones
Individual responses may vary, and long-term safety data in humans remain limited
Weekly measurements of mouse body weight were implemented, and serum glucose levels were monitored