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This activation inhibits intracellular serine/threonine kinases, like JNK, which in turn reduces insulin receptor substrate (IRS)-1 serine phosphorylation, a major contributor to insulin resistance, and decreases atherosclerosis

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Biochem Biophys Res Commun (2004) 325(1):10916

Indications Carnitine Chewable Tablets are used in the treatment of primary and secondary carnitine deficiencies, metabolic disorders of the myocardium in ischemic states