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Both are likely to require either significant real world observation in off-label use, or some form of RCT with careful observation

The AMA sent out about 9000 surveys and an average of 80 SLPs responded

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*Correspondence: Annunziata Nusca, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Cardiovascular and Smooth Muscle Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Physiology, Osmosis