It should be noted that despite the immunophenotype and histological picture similar to melanoma, the tumor is distinguished by the presence of clinical signs of nerve damage (pain syndrome), low proliferative activity according to Ki67, and the absence of mitotic figures at the light-optical level, as well as the absence of invasive growth
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nearly doubles muscle fiber cross-sectional area and increases muscle contractile strength by ~70%, restoring regenerative function to levels comparable to youthful muscle 1
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Western blot assay and real-time reverse transcription polymerase chain reaction further demonstrated that the expression of odonto/osteogenic markers (ALP, RUNX2/ RUNX2 , OSX/ OSX , OCN/ OCN , COL-I/ COL-I , DSPP/ DSP , and DMP-1/ DMP-1 ) in IGF-1 treated SCAPs were significantly upregulated in Let-7c -low group
