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Mediation analysis from the STEP trials found that of the additional 7.6-14.4% weight loss achieved with semaglutide versus placebo, less than 1 percentage point was mediated by gastrointestinal adverse events
It is intended to be administered by subcutaneous or intramuscular injection
What warrants attention and a call to the clinic: persistent nausea beyond the first 10 days, injection site reactions that worsen rather than resolve, or any signs of systemic allergic response
Increase cagrilintide while holding retatrutide
Most people feel a noticeable energy boost within 24 to 72 hours, especially if they were deficient
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