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The new Wegovy pill operates at a higher dose (25 mg) and is approved for weight management rather than glycemic control specifically but the blood sugar effects are real and measurable

While some people may not lose as much weight on GLP-1 medications like semaglutide, they can still experience significant health benefits

Results Semaglutide attenuates LPS-induced neuroinflammation To investigate how GLP-1 receptor activation modulates inflammatory responses in the brain, we first established a model system allowing detailed temporal analysis of neuroinflammatory processes using LPS

3.2 Therapeutic potential in obesity Although the incretin effects of GIPR undoubtedly play a crucial role in preventing postprandial glucose excursion, there is still intensive debate on whether the GIPR should be activated or inhibited for the treatment of obesity