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Despite glutamine's benefits, the use of glutamine as a supplement should be approached with caution
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and the use of antivirals that enhance activation of the Nrf2 transcription factor together with N-acetylcysteine administration restore GSH levels correcting the SARS-CoV-2-mediated impaired GSH metabolism (Aquilano et al., 2014
Immediate contact or emergency evaluation is necessary if patients experience suicidal thoughts or self-harm urges, severe panic attacks with chest pain or difficulty breathing that could indicate a cardiac event, or anxiety so severe it interferes with daily functioning or safety
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