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Adverse events, including a sense of warmth, muscle cramps, low blood pressure, and fainting, can occur after Myers cocktail administration

39.9% with placebo), with nausea, vomiting, and diarrhea peaking during dose escalation and declining thereafter, whereas constipation remained relatively constant

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DSIP cortisol-lowering effects could theoretically interact with corticosteroids or medications affecting the HPA axis