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Notably, in the RA subgroup, which comprised 38% of the total study population, GLP-1 analog use was also associated with a significant reduction in MACE and all-cause mortality

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"Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1)." N Engl J Med

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Early weight loss (weeks 1-4) is slightly slower with microdosing, but outcomes converge by week 12

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Siraj, M

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What helps mitigate loss of lean body mass: Protein: Aim for 1.21.6 2.0 g/kg body weight/day (never less than 0.40.5 g/kg)

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