Likewise, a 2010 phase III, randomized, double-blind, placebo-controlled, parallel-group study undertaken in Europe found that MT1 reduced the severity of PLE when administered as a 16 mg implant over a four-month period [14]
Metabolomic, cytokine, mitochondrial, and natural killer cell meta-analyses have revealed an abnormal but mixed pattern, likely originating from both heterogeneity across patients and study methods (2124)
Participants taking the 12mg dose for 68 weeks lost an average of 28.7% of their body weight
Note that with this method of delivery absorption occurs predominantly in the stomach to achieve therapeutic plasma levels, and overcomes otherwise insurmountable challenges of peptide absorption related to solubility, molecular size, and enzymatic degradation in the protease-rich environment of the small intestine (Buckley et al, 2018)
But heres a pro tip from our labs: for long-term storage of lyophilized powder (meaning you don't plan to use it for several months), a freezer is even better