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Discontinuing GLP-1 therapy often leads to a reversal of its benefits, particularly for weight loss
In addition to promoting weight loss, Semaglutide GLP-1 has been shown to improve metabolic health
Second, kidney injury in diabetes appears to be related to glomerular hyperfiltration [93, 94], which is likely related to an excessive reabsorption of sodium in the proximal tubule, leading diminished delivery of sodium to the macula densa, and (via tubuloglomerular feedback) to afferent arteriolar dilatation [95, 96]
