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The article says the active ingredient and molecular structure are the same, but the source, manufacturing pathway, and regulatory classification are not

Possible involvement of agmatine in neuropharmacological actions of metformin in diabetic mice

Interestingly, a recent study examining the time-dependent effect of low IGF-1 levels on aging outcomes observed that a targeted reduction in liver-derived IGF-1 early (10 d or 5 mo) or later in life (15 mo) improved aspects of lifespan in females, though these effects were most pronounced when IGF-1 was reduced at 5 mo old 19

Hormone Research, 51 (2), 78-84