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These signatures can help distinguish early OA patients from healthy individuals, though large-scale clinical cohort studies and quantitative analyses are still required to verify their sensitivity and specificity

Multi-dose Vials: For ongoing therapy under medical supervision

In the discovery phase (Cohort 1), RBD status was evaluated via validated questionnaires (RBDQ-HK, cutoff of 18 for the diagnosis of RBD, detailed in the Methods section, Supplementary Fig

Results Subject screening and enrollment In all, 31 individuals were screened in order to identify 15 who qualified

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