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Consequently, the study conclusions demonstrate good reproducibility under comparable experimental conditions

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The cellular mechanism by which the releasing hormones affect GH secretion from the somatotrope requires specific signal transduction systems (cAMP and/or calcium influx and/or mobilization of intracellular calcium) and/ or tyrosine kinase(s) and/or nitric oxide (NO)/cGMP

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These interactions play a pivotal role in modulating the activation state of cells comprising the BBB, as well as Ms and microglia, themselves