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Among the macronutrients in the diet, fat is the most calorie-dense, supplying 9 kilocalories per gram, whereas carbs and protein only provide 4 kilocalories per gram

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This metabolic disease involves defects in insulin secretion and action, and is closely linked to obesity, genetic factors, and metabolic inflammation, and its complex pathologic mechanisms are driving the deepening of cutting-edge research in endocrine medicine

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