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The accumulation of LCACs during mitochondrial FAO disorders can inhibit the activity of PPAR/PGC1, destroy the regeneration of peroxisomes, lead to increases in BCAA and ROS levels, and activate the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway
Severe obesity among adolescents and young adults has increased substantially over the past two decades, currently affecting about 9% of people between ages 12 and 18
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Magnesium, together with vitamins B6, B12, niacin (vitamin B3) and vitamin C, actively aid in reducing tiredness and fatigue, as well as in normal energy-producing metabolism
10.1016/j.jff.2026.107165 3 Alegre-AbarrateguiJ.BrimblecombeK
