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doi: 10.1016/s0140-6736(19)31150-x 32 MostafaeiHMoriKHajebrahimiSAbufarajMKarakiewiczPIShariatSF
To measure lifetime use, Gallup asked: Have you ever taken weight loss medications such as semaglutide (brand names Ozempic and Wegovy), liraglutide (brand name Saxenda) or tirzepatide (brand names Mounjaro and Zepbound)? To measure current individual use (if yes to the first question), Gallup then asked: Are you currently taking weight loss medications such as semaglutide (brand names Ozempic and Wegovy), liraglutide (brand name Saxenda) or tirzepatide (brand names Mounjaro and Zepbound)? The Food and Drug Administration (FDA) approved the Novo Nordisk drug Wegovy (semaglutide) for weight loss in 2021
Early research described it as relatively selective for GH release compared with some older secretagogues (Raun et al., 1998)
Perhaps the launch last week of an oral pill version of Wegovy offering both convenience and a lower price could lead to some patients staying on their medications longer
In addition, functional study demonstrated that local injection of GLP-1 into the BNST induces food suppression during the dark phase (Williams et al., 2018)
