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It also helps to correct severe deficiencies very quickly (if the deficiency is not based on genetic abnormalities which may require a specific form(s) of B12)
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The exact amount depends on the patients health, how bad the deficiency is, and how well they respond to treatment
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In this situation, it can be challenging to demonstrate B12 deficiency even when there are typical symptoms (including neuropathy-like paraesthesia and numbness), as serum B12 concentrations may be just within, or sometimes above, the normal range due to the oral supplementation
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