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(2025) discovered that Talaromyces purpurogenus , enriched in the gut of PCOS patients, produces the metabolite AT-C1, which suppresses the AhR signaling pathway and reduces IL-22 secretion, thereby inducing PCOS-like symptoms (69)

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The two goals are often sequenced rather than run at once, with a recovery focus while tissue settles and a growth focus afterward

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