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Measures of adherence as predictors of early and total weight loss with intensive behavioral therapy for obesity combined with liraglutide 3.0 mg
In cells without oxidative stress, Keap1 (Kelch-like ECH-associated protein 1), a cysteine (Cys)-rich protein (27 Cys residues in human and 25 in mouse), normally binds Nrf2 (also called nuclear factor erythroid 2-like 2 or Nfe2l2), a master transcription factor for cellular antioxidant responses, and functions as an adaptor for a Cullin 3 (Cul3)-based E3 ubiquitin ligase complex to promote polyubiquitination and proteasomal degradation of Nrf2 31,32,33,34
Oncogene 26 , 64886498 (2007)
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