In fact, the SELECT trial published in the New England Journal of Medicine found that weekly semaglutide reduced the risk of major cardiovascular death by 20% compared to placebo in adults with overweight or obesity and existing heart disease
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1 Introduction Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from gut enteroendocrine cells in response to food intake, and display insulinotropic actions by stimulating specific G-protein linked GLP-1 receptor (GLP-1R) on the pancreatic cells
Here's every data point from the May 21, 2026 announcement