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In laboratory literature, the copper(II) complex is studied for extracellular matrix remodeling pathways associated with collagen synthesis, glycosaminoglycan production, and growth factor signaling

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5 This alone predicts that a hypothetical AOD-9604 trial enrolling predominantly East Asian participants would show lower mean fat-loss response than a European-ancestry cohort at the same dose, not because the drug works differently pharmacologically, but because a larger fraction of patients would carry the blunting allele

Therefore, it is reasonable to believe that GLP-1R is a potential link between these two diseases