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By pursuing a comprehensive systems approach, it is possible to initiate a fundamental change in GLP-1 RA research, moving from merely treating diseases to promoting an extended healthspan

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One such option is Mounjaro (tirzepatide), a once-weekly injectable medication that was originally approved for type 2 diabetes and is now FDA-approved for weight management in adults with obesity or overweight and at least one weight-related health condition

Astrocytes are direct cellular targets of lithium treatment: novel roles for lysyl oxidase and peroxisome-proliferator activated receptor-gamma as astroglial targets of lithium