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Currently, the most popular approaches employ various transgenic rodent models that exhibit amyloid and tau pathologies, such as Tg2576 [115], APP and presenilin 1 (APP/PS1) [116], Tau/APP [117], J20 [118], 3 Tg [119] and 5 FAD [120] transgenic mice, as well as McGill-R-Thy1-APP [121] transgenic rats

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Yet, its important to note that more research is needed before any definitive conclusions can be made

Peptide therapy typically requires a loading period of 3-6 months for the full effects to become noticeable

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