selenium dependent glutathione peroxidase The role of metabolism and selenoproteins in cartilage homeostasis and arthropathies selenium dependent glutathione peroxidase Small

systematically reviewed the oxidative stress from the perspectives of oxidants and antioxidants, and noted that oxidants with vastly different half-lives may be observed at the site of generation or be transported to distant target sites where they exert oxidant activities in cell metabolism [63]

10.1016/j.bbrc.2011.09.046 Biochem

Bone marrow stroma-derived PGE2 protects BCP-ALL cells from DNA damage-induced p53 accumulation and cell death

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Naturally or synthetic chemotherapeutic agents exert their effects through oxidation or modification of cysteine thiol groups present in the cellular signal molecules mediated by phosphatases and kinases