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Sulfonylurea drugs affect sulfonylurea receptor 1 (SUR 1), which leads to the closure of adenosine triphosphate (ATP)-dependent potassium channels, preventing potassium from leaving the cell and depolarizing the cell membrane, leading to an influx of calcium and triggering insulin release

Puig E, Tolchard J, Riera A, Carulla N (2020) Somatostatin, an In Vivo Binder to A Oligomers, Binds to PFO A(142) Tetramers

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Scalability: Transition from small-scale synthesis to large scale manufacturing while maintaining consistency and quality is challenging AGENDA Accelerating Method Development and QC with LC-UV-MS for GLP-1 Agonists Steve Calciano Characterisation of GLP-1 Peptides and Impurities using HRMS and Ion Mobility Jon Fox Light Scattering solutions to analyse oligomeric state and aggregation in GLP-1 formulations Sophia Kenrick Bio-Analytical Quantification of GLP-1 Peptides: A Case Study on Semaglutide Henry Foddy Panel Discussion with All Speakers Why Attend