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Additionally, angiotensin-converting enzyme 2 (ACE2) is a cardioprotective enzyme within the renin-angiotensin system, and its overexpression mitigates chronic hypoxia-induced PH (Oliveira et al., 2023)

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135 described a pathway involving amino-acid- but not insulin-stimulated binding of the small GTPase Rab1A and mTORC1 with subsequent recruitment to Golgi membranes where mTORC1 gets activated by Rheb

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