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L-ascorbic acid (the most potent form of topical vitamin C) requires a low pH, typically around 2.5 to 3.5, to remain stable and penetrate the skin

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While antibiotics effectively eliminate harmful pathogens, their indiscriminate targeting also affects beneficial bacteria, reducing microbial diversity and increasing the likelihood of antibiotic resistance (Lathakumari et al., 2024)

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The peptide research section covers these mechanisms in greater detail for those wanting deeper scientific understanding