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Fatty liver disease In 2025, Wegovy received an additional FDA approval for the treatment of noncirrhotic metabolic dysfunction-associated steatohepatitis (MASH) a serious form of fatty liver disease driven by insulin resistance

At 1 month postprocedure, 7 patients had an average weight regain of 1.2% compared to approximately 3% that is typically seen during this time frame for patients who discontinued GLP-1 medication

Additionally, peptides may have poor oral bioavailability, often requiring specialized delivery methods