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The objective of this review is to provide a comprehensive and structured synthesis of the immunopathogenesis of HT, integrating established knowledge with emerging research areas including oxidative stress, gut microbiota, and epigenetic modifications, while also summarizing current clinical, diagnostic, and therapeutic perspectives (Fig
PTL conceived the study, participated in its design, and coordination, and helped to draft the manuscript
Fujiwara, H., Hirata, K., Takeda, T., The macrolide antibacterial Roxithromycin reduces bronchial hyperresponsiveness and superoxide anion production by polymorphonuclear leukocytes in patients with asthma, J
doi: 10.3389/fonc.2020.00779 344
doi: 10.21037/jgo-22-917 11 ViennetMTapiaSCottenetJBernardAOrtega-DeballonPQuantinC
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