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Peer review Peer review information Nature Reviews Urology thanks Ralf Henkel, Sandro Esteves and Luca Boeri for their contribution to the peer review of this work
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usage of other skin-lightening agents within one month prior to the study
This pattern of regulation suggests a shift toward more favourable nitric oxide (NO) production, as eNOS and nNOS are typically involved in the generation of low, physiological levels of NO, which play key roles in maintaining vascular tone, blood flow, and neuronal function [68, 69]
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