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NaV1.7 was once considered one of the most promising targets for non-opioid pain management after the discovery that individuals with loss-of-function mutations are insensitive to pain yet are otherwise healthy

This blog explores the science behind GLP-1 plateaus , why they occur, and what providers can do to prevent, reverse, or bypass them through smart cycling strategies, metabolic support, and adjunctive protocols like SLM+

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