Journal of Controlled Release 161 , 505522, (2012)
Su G, Yang W, Wang S, Geng C, Guan X
The impurity caused by the interaction between B12 and compounded tirzepatide is concerning because nothing is known about its short- or long-term effects in humans, the potential impact on the drugs interaction with the GLP-1 and GIP receptors, toxicity, immune reactions, or how it is absorbed, distributed, metabolized and eliminated
This is mainly through the adrenal glands producing stress hormones such as cortisol
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