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Exendin-4 exposure also led to a significant reduction in the level of reactive oxygen species (ROS) in Control shRNA islets exposed to thapsigargin, but this effect was no longer present in SPHKAP shRNA-transduced islets, which presented with basally higher ROS levels than the corresponding control islets (Fig
Thats exactly the conversation worth having with a rheumatologist who understands both inflammation and metabolic health
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