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The new NICE guidelines recommend healthcare professionals offer B12 blood tests to anyone with at least one symptom or sign and one or more risk factors
But cagrilintide won decisively on tolerability: GI adverse events 54.0% vs 73.8%, and discontinuation for adverse events 2.6% vs 3.6% (cagrilintide was actually below the 3.5% placebo rate)
Baseline kidney function, liver markers, pancreatic enzymes and blood glucose are the ones named, since visual inspection is only one layer of safety
Patients should set realistic expectations, track progress, and prepare for possible revisions
doi: 10.3390/metabo13040493
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