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For most hair loss patients, topical delivery still reaches the follicles more directly and stays the preferred approach unless there is a specific systemic indication

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Up to this point, we have ignored the fact that some drugs follow more complex multicompartment pharmacokinetics, eg, the distribution process illustrated by the two-compartment model in Figure 32

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FOXO4-DRI appears to work by inhibiting FOXO4-p53 binding