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The induction of targets, such as GCL, requires the activation of upstream transcriptional co-activators

Immunohistochemistry images were quantified by staining intensity using ImageJ

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Moreover, insulin sensitivity indices, frequency of hypoglycemia, and formal quality of life assessments (eg, validated PRO instruments) were not incorporated into the study protocol due to resource and logistic constraints

Vos has recently identified phenotypes of MASLD (Nature Communications), which she hopes will better drive individualized treatment in kids