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Sbodio JI, et al

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This could suggest an overactive Gln-Glu cycle in adults with ASD, which may represent either a manifestation of, or a compensatory response to, dysregulated excitatory neurotransmission implicated in the pathophysiology of ASD

For patients on stable antidepressant regimens, that reduction can destabilise mood within two to three weeks, often before the patient or prescriber connects it to the GLP-1 medication