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It is reported here that the NADPH antimetabolite 6-amino-NADP (6AN) was cytotoxic to cultured adult rat spinal cord oligodendrocyte precursor cells (OPCs) as well as OPC-derived oligodendrocytes

Median survival after primary diagnosis is ~14 months when following standard treatment regimens (Goodwin and Laterra, 2010

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Anabolic steroids (exogenous [from outside the body] testosterone and testosterone-like drugs) used by some athletes and body builders suppress hormonal signals from the brain that are needed to stimulate normal sperm production and maturation

Additionally, no significant age-related differences in serum GR activity were observed among men, whereas significant differences were noted among women