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In 2024, Demir-Dora et al
The proportion of participants with resistant hypertension at baseline (n=167) that reached BP targets at week 68 was 42.0% and 29.3% for CagriSema and placebo, respectively (odds ratio, 1.7 [95% CI, 0.74.4])
LRRK2 is an enzyme with both kinase and GTPase activities (Berwick et al., 2019)
No large-scale, long-term human trials exist to fully understand its safety profile
Skin aging (reduced collagen, wrinkles): Fibroblasts lose repair capacity, leading to extracellular matrix degradation
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