This action minimizes the shift to less efficient anaerobic respiration, preserving cellular energy and reducing oxidative damage ( 9 )
Dehydration, however, can impair these processes, leading to a slower metabolic rate and prolonged presence of alcohol in the body
This is a commonly referenced study from 1963 claiming a half-life of 5-6 days: nature.com/articles/198200a0 Although I would not cite it as an authority, the six-day half-life has also made it onto the B12 page in Wikipedia, seemingly unchallenged
[1] The peptide has been studied for its potential in mitigating cell aging, inducing protein synthesis, minimizing free-radical damage, preventing bacterial infection, and improving the function of skin fibroblasts
The European Association for the Study of the Liver (EASL) clinical practice guidelines on Wilson disease note that hepatic copper exceeding 250 mcg/g dry weight is a strong diagnostic criterion for Wilson disease, but subclinical copper accumulation can begin at much lower thresholds in patients with cholestatic or cirrhotic liver disease [2]
