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doi: 10.1073/pnas.0702854104 99

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Las principales exclusiones incluyen aquellos con cirrosis heptica (fibrosis estadio F4), individuos con antecedentes personales o familiares de carcinoma medular de tiroides o sndrome de neoplasia endocrina mltiple tipo 2, y personas con obesidad delgada (Lean MASH), donde la eficacia y seguridad del tratamiento no estn demostradas