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GLP-1 medications like semaglutide have shown remarkable efficacy for weight management, with clinical trials demonstrating up to 22% body weight reduction over 68 weeks
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Clinical trials of sodiumglucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide 1 (GLP1) receptor agonists have shown beneficial effects of these agents on kidney outcomes in patients with type 2 diabetes mellitus
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Sleep changes (if present) tend to stabilize
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