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In the structures of human and yeast GS, two alanine residues form van der Waals contacts with the glycine moiety of glutathione (Polekhina et al., 1999
However, SCFAs, predominantly butyrate, can enhance gut barrier integrity, thereby reducing intestinal permeability and systemic inflammation
DNA Repair (Amst) 3, 959967
Discovered in 1888, Glutathione (GSH) is an important antioxidant in plants, animals, fungi, and some bacteria